Document Type
Article
Publication Title
Dermatology Online Journal
Abstract
Perivascular epithelioid cell tumors, also known as PEComas, are mesenchymal neoplasms which uncommonly originate within the skin, with only 23 cases documented within the literature. These rare neoplasms classically display epithelioid cells composed of granular or clear cytoplasm arranged in sheets, nests, or cords. Their immunoreactivity for melanocytic and smooth muscle markers makes these tumors distinct and unigue. We herein present two cases of primary cutaneous PEComas that clinically mimic other common cutaneous neoplasms and illustrate the necessity for clinical-pathologic correlation. A literature review is also presented to compare the different clinical and histological presentations of cutaneous PEComas.
DOI
10.5070/D3271055626
Publication Date
10-2021
Keywords
Epithelioid cell, Mesenchymal neoplasm, PEComa, Perivascular epithelioid cell tumor
ISSN
1087-2108
Recommended Citation
Wong J, Mammino J, Seyffert J, Schmits K, Marks E, Rivlin D. Primary Cutaneous Perivascular Epithelioid Cell Tumors: Two Cases and a Review of the Literature. Dermatology Online Journal. 2021; 27(10). doi: 10.5070/D3271055626.
