Hereditary angioedema (HAE) manifests due to a deficiency of the C1-esterase inhibitor and can present with life-threatening swelling of multiple body regions such as the face, hands, upper respiratory tract, and intestinal walls. The present case describes the manifestation and symptomatic exacerbation of HAE in a multiparous Caucasian female. Very few trials and cases are available on HAE exacerbations during pregnancy, and our case describes the timeline and treatment in order to add to the clinical awareness of the disease. It is necessary to treat these patients rapidly to avoid unnecessary morbidity and interventions. For the time being, our patient has been appropriately managed with icatibant.
hereditary angioedema, pregnancy
Sankrithi P, Shah K, Bernabe CC. Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female. Cureus. 2020; 12(5). doi: 10.7759/cureus.8006.