Collagenous Colitis With Mucosal Ulcerations in a Patient Without Nonsteroidal Anti-Inflammatory Drug or Lansoprazole Use

Authors

Andrew C. Berry, Kansas City UniversityFollow
Rahman Nakshabendi, University of Florida
Hussein Abidali, Banner Good Samaritan Medical Center
Cassandra Johnson, University of South Florida
Kevin Dholaria, University of Miami
Danny J. Avalos, University of Miami
Aaron C. Baltz, GI Associates

Document Type

Article

Publication Title

Annals of Gastroenterology

Abstract

Chronic watery diarrhea combined with normal-appearing colonic mucosa at endoscopy with abnormal histopathology is classified as microscopic colitis. Microscopic colitis encompasses both collagenous and lymphocytic colitis. A 42-year-old Caucasian woman presented with severe diarrhea for six weeks with loose watery stools every 1-2 h, approximately 15 episodes per day. She denied any melena or significant abdominal pain. She denied nonsteroidal anti-inflammatory drug or lansoprazole use, and was only taking diphenoxylate/atropine for her symptoms. Colonoscopy revealed superficial ulcerations in the distal ascending and transverse colon and scattered ulcerations in the descending and sigmoid colon, with biopsy confirming collagenous colitis. We report a rare case of collagenous colitis accompanied by mucosal ulcerations in the absence of known culprits of mucosal ulcerations, such as nonsteroidal anti-inflammatory drugs or lansoprazole.

Publication Date

7-2015

Keywords

Diarrhea, colitis, colonoscopy

ISSN

1792-7463

Recommended Citation

Berry AC, Nakshabendi R, Abidali H, Johnson C, Dholaria K, Avalos DJ, Baltz AC. Collagenous Colitis With Mucosal Ulcerations in a Patient Without Nonsteroidal Anti-Inflammatory Drug or Lansoprazole Use. Annals of Gastroenterology. 2015; 28(3).