Effects of Local Anesthetics and Contrast Agents on Musculoskeletal Regenerative Medicine Procedures
Document Type
Article
Publication Title
Regenerative Medicine
Abstract
In regenerative medicine, cells, tissues and organs are often replaced, engineered or regrown in order to restore their function after they have been damaged or lost. Local anesthetics, corticosteroids and contrast agents are commonly employed for both diagnostic and therapeutic objectives in interventional pain and musculoskeletal treatments for regenerative medicine. There is growing evidence that routine injectables promote catabolism and disease processes. Thus, understanding the effects of these compounds on regenerative medicine injectates and target tissues such as tenocytes, chondrocytes, nucleus pulposus and ligamentous tissue is critical. This review includes the current research on the effects of local anesthetics and contrast agents, as well as their use and recommendations in regenerative medicine operations.
DOI
10.2217/rme-2021-0176
Publication Date
11-2022
Keywords
anesthetic, cartilage, contrast agent, lidocaine, ligament, musculoskeletal, nucleus pulposus, regenerative procedure, safety, tendon
ISSN
1746-076X
Recommended Citation
Zhang A, Wang D, Diwan S, Lin C, Calodney A, Rosenthal R, Chien GC. Effects of Local Anesthetics and Contrast Agents on Musculoskeletal Regenerative Medicine Procedures. Regenerative Medicine. 2022; 17(11). doi: 10.2217/rme-2021-0176.
