ED50

Document Type

Article

Publication Title

StatPearls

Abstract

The ED50 (median effective dose) is the dose of a medication that produces a specific effect in 50% of the population that takes that dose. This number has common use as what a clinician or patient can expect for a drug effect, but clinicians may use a different dosage for their particular intended effect, depending on the balance of need or benefit of the drug versus the toxicity of the drug. The toxic dose in 50% of the population is called TD50; the ED50 should hopefully be much less than the TD50, as this would indicate an effective medication at a lower dose.

Publication Date

9-24-2022

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