Journal of Pharmacognosy and Phytochemistry
This paper highlights the novel antibacterial properties of Coleus scutellarioides against certain species of the domain bacteria, of which no Coleus antimicrobial activity was previously demonstrated. Coleus has demonstrated antimicrobial properties against many species of bacteria and fungi. However, the search for novel antimicrobial compounds is vital in this age of growing microbial resistance. Samples of Coleus extraction were carried out with 95% ethanol and the filtrate was impregnated into sterile discs. The extraction solvent (95% ethanol) alone was also impregnated into sterile disc as vehicle control. Discs of Coleus extracts or control were placed on bacterial and fungi plates and the zones of inhibition were measured. Coleus leaves displayed novel antimicrobial activity against S. agalactiae and S. pyogenes. Coleus stems displayed antimicrobial activity against S. pyogenes. This research demonstrated novel Coleus activity against S. pyogenes and S. agalactiae, which had not been previously demonstrated.
Drug resistance, antimicrobial, gram-negative, gram-positive, bacteria
Puga TB, Schafer J, Schiefelbein CQ, Islam N, Agbedanu PN. Novel Coleus Antimicrobial Activity Against S. agalactiae and S. pyogenes. Journal of Pharmacognosy and Phytochemistry. 2022; 11(4). doi: 10.22271/phyto.2022.v11.i4a.14440.