Document Type
Article
Publication Title
Gynecologic Oncology Reports
Abstract
Non-gestational ovarian choriocarcinoma (NGOC) is a rare phenomenon seldom reported in the literature. Patients often present with abdominopelvic pain, and sometimes a palpable adnexal mass. Surgical excision is paramount in treating this malignancy; however, fertility-preserving care is a debated topic among gynecologic oncologists. Most patients reported in the literature are nulliparous women of child-bearing age. It is important to consider fertility preservation whilst balancing oncologic outcomes. We present a case of an 18-year-old nulliparous female with stage IIB NGOC that had disease progression in the lungs and pelvis shortly after undergoing fertility-preserving surgery. She required emergent completion surgery and received etoposide (E), methotrexate (M), actinomycin-D (A), cyclophosphamide (C) and vincristine (O) (EMA-CO) with complete response. She remains disease-free after 21-months.
DOI
10.1016/j.gore.2023.101312
Publication Date
11-30-2023
Keywords
Non-gestational ovarian choriocarcinoma, Fertility-sparing laparoscopic debulking surgery, Yolk-sac tumor, Case report, Literature review
ISSN
2352-5789
Recommended Citation
Maybury EK, Gwacham NI, Singh C, Mondo S, Ahmad S, McKenzie ND. Rapid Recurrence of Stage IIB Non-Gestational Ovarian Choriocarcinoma with Minor Yolk Sac Tumor: A Rare Case Report and Literature Review. Gynecologic Oncology Reports. 2023; 50. doi: 10.1016/j.gore.2023.101312.
