Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case

Authors

Geoffrey B. Lobban, University of Missouri-Kansas City
Alex J. Luke, University of Missouri-Kansas City
Peter Basta, Research Medical Center
Katsiaryna Laziuk, Research Medical Center
Amandeep Kalra, Research Medical Center
Ashish Kulhari, Kansas City University

Document Type

Article

Publication Title

Cureus

Abstract

Primary central nervous system lymphoma (PCNSL) is an uncommon malignancy of B-cell origin that typically involves the brain, eyes, and spinal cord without systemic spread. PCNSL typically involves the cerebral hemispheres, basal ganglia, or periventricular region. Isolated leptomeningeal PCNSL without any evidence of parenchymal involvement is very rare. We present a very unusual case of PCNSL presenting as persistent bilateral Bell's palsy and trigeminal neuralgia with magnetic resonance imaging (MRI) brain showing significantly hypertrophied enhancing bilateral facial and trigeminal nerves.

DOI

10.7759/cureus.41561

Publication Date

7-8-2023

Keywords

Bells palsy, CNS lymphoma, isolated cranial nerve palsy, trigeminal nerve biopsy, trigeminal neuralgia

ISSN

2168-8184

Recommended Citation

Lobban GB, Luke AJ, Basta P, Laziuk K, Kalra A, Kulhari A. Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case. Cureus. 2023; 15(7). doi: 10.7759/cureus.41561.