Mice Inoculated with Marek's Disease Tumor Cells: Increased Number of Lymphomas

Document Type

Article

Publication Title

Comparative Immunology, Microbiology and Infectious Diseases

Abstract

Germfree derived CFWwd mice were inoculated with tumor cells from chickens with Marek's disease and observed for any long term effect. Nineteen per cent of these animals developed tumors whereas the incidence in control animals was 0.2%. Of those animals which developed tumors, 62% of the animals were observed to have ataxia before tumor development. Marek's disease herpesvirus was never observed in any of the murine tumors.

DOI

10.1016/0147-9571(81)90025-4

Publication Date

1981

Keywords

Marek's Disease, Murine lymphomas

ISSN

0147-9571

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