Document Type
Article
Publication Title
Cureus
Abstract
High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of ovarian cancer, most commonly originating from the epithelium of the fallopian tube. In metastasis of HGSOC cells, there is a particular predilection for the omentum. Metastatic involvement of extraperitoneal lymph nodes, particularly the inguinal region, is rare and may pose a diagnostic challenge. We report a case of an 87-year-old female patient presenting with a right inguinal mass, in whom the pathology of the surgically removed mass confirmed the diagnosis of metastatic HGSOC, requiring oncological follow-up and management. This atypical pattern of spread underscores the importance of considering a Müllerian primary in the differential diagnosis of unexplained inguinal adenopathy and highlights the role of histopathology and immunohistochemistry in establishing the correct diagnosis.
DOI
10.7759/cureus.106024
Publication Date
3-28-2026
Keywords
atypical metastasis, extraperitoneal metastasis, high-grade serous ovarian carcinoma, inguinal mass, ovarian carcinoma metastasis
ISSN
2168-8184
Recommended Citation
Kaufman OR, Agarwal I, Stewart MW, Davis PE, Dunbar B. Unexplained Inguinal Adenopathy Leading to the Diagnosis of Metastatic High-Grade Serous Ovarian Carcinoma. Cureus. 2026; 18(3). doi: 10.7759/cureus.106024.
