Document Type

Article

Publication Title

Cureus

Abstract

We report a case of advanced-stage ovarian carcinosarcoma (OCS) with extensive extra-ovarian involvement and widespread high-grade serous carcinoma involving the omentum, bladder, ileal mesentery, and small bowel serosa in a female patient in her mid-40s. This case highlights a rare arrangement of histologic features and disease differentiation. The metastatic sites demonstrated predominantly epithelial high-grade serous carcinoma, while the sarcomatous component was identified in the adnexal tumor and left pelvic sidewall. The presence of neuroendocrine differentiation, however, represents a rare and infrequently reported histopathologic feature. The case demonstrates the importance of comprehensive histopathologic and immunohistochemical evaluation in accurately characterizing complex gynecologic malignancies.

DOI

10.7759/cureus.115904

Publication Date

9-7-2026

Keywords

figo stage iiic, metastatic, neuroendocrine differentiation, ovarian carcinosarcoma, peritoneal spread, sarcomatous

ISSN

2168-8184

Download

Share

COinS