Document Type
Article
Publication Title
Cureus
Abstract
Histoplasmosis is a common mycosis in North and Central America caused by Histoplasma capsulatum. Affected patients typically remain asymptomatic. However, in some individuals, histoplasmosis can present as a severe illness, usually occurring in patients with underlying risk factors such as the immunocompromised (e.g., acquired immunodeficiency syndrome (AIDS), treatment with immunosuppressive agents), and the elderly without underlying immunocompromised conditions. Here, we present a case of disseminated histoplasmosis diagnosed as an incidental finding on bone marrow biopsy while treating a hospitalized patient for hemophagocytic lymphohistiocytosis. The patient presented with weight loss, anorexia, fatigue, and generalized weakness. The patient was successfully treated with amphotericin B and eventually transitioned to itraconazole.
DOI
10.7759/cureus.36404
Publication Date
3-20-2023
Keywords
opportunistic fungal infection, complication of rheumatoid arthritis, rheumatoid arthritis, ra, infectious disease pathology, histoplasmosis in bone marrow
ISSN
2168-8184
Recommended Citation
Pellegrino RA, Naik R, Bali A. An Interesting Case of Disseminated Histoplasmosis in a Patient With Hemophagocytic Lymphohistiocytosis. Cureus. 2023; 15(3). doi: 10.7759/cureus.36404.
