Adverse Effects of Grape Seed Extract Supplement: A Clinical Case and Long-Term Follow-Up
Document Type
Article
Publication Title
Journal of Dietary Supplements
Abstract
Grape seed extract (GSE) supplement use is becoming more popular today for its potential chemopreventive and chemotherapeutic role. We report a 49-year-old male who presented with recurrent nausea, vomiting, diarrhea, and acute weakness following GSE use. A thorough medical workup ensued and no causes were identified clinically, procedurally, or with imaging. Symptoms resolved after GSE discontinuation and the patient remained symptom-free 5 years later. This case illustrates the paucity of documented detailed clinical cases and lack of controlled trials detailing a thorough and reproducible adverse effect profile of GSE supplement.
DOI
10.3109/19390211.2015.1008617
Publication Date
2016
Keywords
chemopreventive, grape seed extract, nutrition, supplements
ISSN
1939-022X
Recommended Citation
Berry AC, Nakshabendi R, Abidali H, Atchaneeyasakul K, Dholaria K, Johnson C, Kishore VA, Baltz AC. Adverse Effects of Grape Seed Extract Supplement: A Clinical Case and Long-Term Follow-Up. Journal of Dietary Supplements. 2016; 13(2). doi: 10.3109/19390211.2015.1008617.
