Pediatric Neurodegenerative White Matter Processes: Leukodystrophies and Beyond
Document Type
Article
Publication Title
Pediatric Radiology
Abstract
Pediatric neurodegenerative white matter processes are complex, numerous and result from a vast array of causes ranging from white matter injury or inflammation to congenital metabolic disorders. When faced with a neurodegenerative white matter process on neuroimaging, the first step for the radiologist is to determine whether the findings represent a congenital metabolic leukodystrophy or one of various other white matter processes. In this review we first describe a general approach to neurodegenerative white matter disorders. We will briefly describe a few white matter diseases that mimic metabolic leukodystrophies. In the second half of the review we discuss an approach to distinguishing and classifying white matter leukodystrophies
DOI
10.1007/s00247-008-0817-x
Publication Date
7-2008
ISSN
1432-1998
Recommended Citation
Phelan JA, Lowe LH, Glasier CM. Pediatric Neurodegenerative White Matter Processes: Leukodystrophies and Beyond. Pediatric Radiology. 2008; 38(7). doi: 10.1007/s00247-008-0817-x.